Discussion on Mold Toxins and Poultry Intestines

Discussion on Mold Toxins and Poultry Intestines

     We know more than 500 kinds of mold toxins. Among them, there are six mold toxins that have six kinds of mold toxins are traditionally considered to be harmful, they are: AFB1, T2 / HT2, Oclaidotoxin A, Zearalenone, Fumonisin FB, Vomitoxin.

     There are many experimental reports and papers on the harm of mycotoxins to poultry. Such as : T2toxin caused by oral ulcers, AFB1 caused by liver damage, growth retardation, Ochratoxin A caused by kidney damage.

     Consolidated industry survey reports of mycotoxins, feed raw material contamination of at least one mycotoxin is indeed common. However, as feed enterprises implement stricter management in quality control, mycotoxin detection equipment is more and more widely used, and raw materials with particularly high mycotoxin pollution levels are rarely directly used for feed processing. Poultry diets are usually composed of a variety of feed ingredients, so in actual feed production, the more common situation is : poultry diets usually contain a variety of mycotoxins, but each mycotoxin pollution level is not very high, below the national or enterprise risk control limits. The question is : is such feed really safe ?

     Poultry first contacts mold toxins is the digestive tract, where small intestines are primary. Mycotoxins are basically small molecular compounds, and even when the content is very low, it can also be directly absorbed into the body by intestinal epithelial cells. Intestinal epithelial cells becomes a primary goal of a bacterial toxin attack. After almost all mold toxins enter the intestinal epithelial cells, on the one hand, it will destroy the tightly linked protein composite structure, and it will also hinder the repair of the tight connection structure, resulting in serious damage to the tight connection structure. After the tight connection structure is damaged, the beside permeability of the intestinal epithelial cells increases, thereby producing a series of chain reactions.

     In summary, the result of being destroyed in the intestinal epidermal connection, resulting in:

1. The ability of intestinal absorption nutrients decreased;
2. The intestinal barrier function is lowered, the pathogenic bacteria in the intestinal cavity can enter the body circulation system, while the nutrients in the body can flow into the intestinal cavity;
3. Intestinal microbial flourization;
4. The intestinal immune system is excessively activated by pathogenous bacteria, antigen, endotoxin. On the one hand, energy is consumed, and on the other hand, it has caused immunosuppression to vaccines or specific microorganisms.

     Toxin Killer is a self-developed aflatoxin degrading enzyme that can degrade AFB1, the enzyme is expressed by pichia pastoris, and produced by deep fermentation.

     Welcome to consult if you have any questions.