Aquatic Application of Clostridium Butyricum

Aquatic Application of Clostridium Butyricum

In the new era of increasing pressure on food safety and environmental protection, changing the mode of aquaculture production and promoting green production of aquaculture are the basic requirements for the sustainable development of the aquaculture industry. Probiotic products have gradually become the most potential alternatives to antibiotics due to the advantages of green environmental protection, non-toxic side effects, non-residue, wide range of effects, and non-drug resistance.

The metabolites of Clostridium butyricum include enzymes, vitamins, hydrogen, organic acids, Clostridium butyricum, short-chain fatty acids, etc. These metabolites can play a good role in aquaculture.

Enzymes and vitamins : Clostridium butyricum can not only produce B vitamins, vitamin K and other substances in the intestine, but also produce amylase, protease, glycosidase, phospholipid synthase, lipase and other enzymes. Under the action of these enzymes Clostridium butyricum fermentation to produce glucose, maltose, etc., which helps the body ' s digestion and absorption, promote the growth and reproduction of probiotics ; at the same time, Clostridium butyricum can also produce enzymes that degrade non-starch polysaccharides in plant feed, such as pectinase, cellulase, glucanase and other substances, and participate in various metabolisms in vivo, which can promote the comprehensive absorption of host intestinal nutrition and improve animal production performance. In addition, certain oligosaccharides produced provide nutrients for other probiotics. The addition of Clostridium butyricum in feed can promote the increase of intestinal epithelial cells in shrimp, and enhance the absorption and transformation of nutrients such as vitamins, amino acids, calcium, phosphorus, iron and selenium in aquatic animals and shrimp.

Hydrogen production : enhancing antioxidant enzyme activity and reducing oxidative stress ; anaerobic environment was created.

Organic acids : reducing intestinal pH, inhibiting pathogen growth, and reducing enterotoxin ; intestinal epithelial energy supply, promote cell proliferation, repair and regeneration of intestinal mucosal barrier ; improve the intestinal morphological structure, enhance the absorption capacity of nutrition ; regulating the expression of galectin-1 gene to prevent intestinal cancer ; regulation of mucus mucin, tight junction protein gene expression, enhance physical barrier, resist harmful microbial invasion.

Clostridium butyrate : kill Clostridium welchii and Clostridium difficile enteritis-related pathogenic Clostridium for treatment of diarrhea ; as immune effector molecules, regulating host immune defense system can enhance immune function.

Short-chain fatty acids : Clostridium butyricum has a unique metabolic mode, which can ferment sugars to produce large amounts of butyrate, acetic acid and lactic acid, as well as a small amount of short-chain fatty acids such as propionic acid and formic acid. In the gastrointestinal tract, short-chain fatty acids can not only reduce its pH value, but also be directly absorbed in the production site, and stimulate intestinal peristalsis, which is helpful in the treatment of related diseases. For example, the addition of Clostridium butyricum in crustacean compound feed can effectively reduce the probability of white feces and laxation of crustaceans, greatly reduce the occurrence of jejunum jejunal empty stomach of Litopenaeus vannamei, inhibit the apoptosis of intestinal epithelial cells and the inflammatory response of intestinal mucosa, such as intestinal atrophy, bending, intestinal rupture, laxation and redness. Butyric acid and lactic acid are the probiotics of bifidobacteria, which are the dominant intestinal probiotics of shrimp. They can promote the rapid proliferation of bifidobacteria in shrimp and stabilize the intestinal microenvironment. It is effective to prevent and treat shrimp early death syndrome.

Henan New Yanghao Biotechnology is the source manufacturer of Clostridium butyricum. It is a national high-tech enterprise that has obtained the production qualification of Clostridium butyricum feed additives. Fermentation capacity ranks the top three in the country. If you have any problems, you can contact us at any time.